Back at the end of 2007, Privacy International published this map of world surveillance societies. The full report is here.  Each country is rated on a number of categories, and the results pooled to give an overall rating.  The dear old United Kingdom doesn't come out of the analysis too well.

As I posted the other day, the latest version of Ubuntu GNU/Linux has been released.  Ubuntu's schedule sees a new release every six months, and this is reflected in the release numbering: 7.10 was released in October 2007, 8.04 in April 2008 and 8.10 in October 2008.  Each release has a nickname - 8.10 is also known as 'Intrepid Ibex', hence the image of an ibex to the left.

I usually avoid fresh installs of Ubuntu, preferring to go the route of upgrading via synaptic.  This involves considerable file downloading, which can be a fairly lengthy affair, particularly soon after release date when the Ubuntu servers and their mirrors are presumably havily loaded.   I have four computers running Ubuntu, and in light of the usual comments and complaints in the Ubuntu forums, I thought I'd note my upgrade experiences here.

The BBC are reporting that an initiative to curb drug use in Aberdeen will test pub-goers for drug use.  It's a relatively non-invasive test involving hand swabs.  Te odd thing about this is the way the test is being carried out.

People are tested when entering pubs and clubs: the test is apparently not compulsory, but those declining to be tested will be refused entry.  An unusual definition of "not compulsory", that!  So, let me get this right.  I could be lawfully going about my business, and wish to visit a pub for a beer.  I can be stopped for drug testing, and on declining to be tested will be refused entry.

Further evidence of abuse of the Regulation of Investigatory Powers Act (RIPA) is reported by the Daily Telegraph (1/11/08).  Their investigation involved FOI requests to councils: over half of them are using RIPA powers for such trivia as monitoring abuse of refuse collection, littering and fly-tipping.

This is far from the first such occasion: earlier this year, Poole Borough Council spied on a family to check if they live in a school catchment area.  (BBC News 10/4/08), and Bury Metropolitan Council spied on their binmen to catch them over-enthusiastically collecting refuse (The Register 10/9/08) -an action that cost the council a £100,000 settlement - three days before the case was due to go to trial.

An amino acid polymorphism in the couch potato gene forms the basis for climatic adaptation in Drosophila melanogaster

Most organisms are faced with dealing with seasonal variations in environmental conditions.  As winter approaches, physiological changes need to be implemented: deciduous trees drop their leaves, mammals may hibernate, and so forth.  In the case of many insects, the strategy is to move into a diapause state.  This may be in any of the life stages - pupal diapause, larval diapause etc, and in the case of Drosophila melanogaster reproductive diapause, in which ovarian activity is shut down in response to a combination of short day length and low temperature.  My interests in diapause are two-fold in origin: firstly, diapause appears to have an impact on lifespan in Drosophila, and secondly, my father identified the existence of reproductive diapause in Drosophila back in 1989.  

"Privacy is in our DNA, so we need to be honest and clear about what we are doing. We have decided not to be in Phorm because of that... The way it was proposed, the privacy issue was too strong." 

Just thought I'd plug the new release of Ubuntu Linux: Version 8.10, Intrepid Ibex.  Ubuntu Linux is the linux distribution that I use on my work laptop and three PCs at home.  In my view it's a fully featured and fully functional operating system, and well worth investigating. The press release is here.

I choose Ubuntu for a number of reasons, including ease of installation, software installation and upgrades. And of course it's open source and a free download  I'm well aware of the numerous alternative versions of Linux out there, and that some of those may better suit other users.  check out the distrowatch site for more information.   Many thanks to all the developers that together enable the distribution of so many flavours of Linux.

We've had another paper on the WRN exonuclease homologue accepted for publication.  In it we demonstrate that DmWNexo is a 3'-5' exonuclease, and describe a new EMS allele. Here's the abstract:

The premature human ageing Werner's syndrome is caused by loss or mutation of the WRN helicase/exonuclease. We have recently identified the orthologue of the WRN exonuclease in flies, DmWRNexo, encoded by the CG7670 locus, and showed very high levels of mitotic recombination in a hypomorphic PiggyBac insertional mutant. Here, we report a novel allele of CG7670 , with a point mutation resulting in the change of the conserved aspartate (229) to valine. Flies bearing this mutation show levels of mitotic recombination 20-fold higher than wild type. Molecular modelling suggests that D229 lies towards the outside of the molecule distant from the nuclease active site. We have produced recombinant protein of the D229V mutant, and assayed its nuclease activity in vitro, and compared activity with that of wild type DmWRNexo and a D162A E164A double active site mutant we have created. We show for the first time that DmWRNexo has 3′ -5′ exonuclease activity and that mutation within the presumptive active site disrupts exonuclease activity. Furthermore, we show that the D229V mutant has very limited exonuclease activity in vitro. Using Drosophila , we can therefore analyse WRN exonuclease from enzyme activity in vitro through to fly phenotype, and show that loss of exonuclease activity contributes to genome instability. 

The BBC reports that measures to prevent undesirables gaining access to the UK are to be strengthened, under measures to be introduced by our not-so-libertarian Home Secretary.

At least the plan is to announce who's on the the list of over 230 individuals considered to be a threat to the UK.   The measures  are as follows:

The British Humanist Association have teamed up with Richard Dawkins to push a message on London buses. 

It's apparently in response to previous pro-religion bus advertising (see Ariane Sherine's comment article at The Guardian). You can donate to the campaign here.   Fund raising has exceeded expectations - perhaps the campaign with run and run (round and round?).  As of 28/10/08: